Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Font Size

What nonprescription sleep medicine can I take while pregnant?

Pharmacologist, WebMD Medical Expert
American Pharmacists Association

Diphenhydramine is a  commonly used OTC product. It is an antihistamine medication with one side effect profile of drowsiness. It is found as the active ingredient by itself or in combination products with pain relief medications, such as acetaminophen or ibuprofen.

If you are pregnant and have trouble sleeping, first consult your ob-gyn before taking any medications. Diphenhydramine has a pregnancy risk category B, which means studies have not been able to prove an increased risk of fetal abnormalities.

If you were to select an OTC product for aid with sleep, stay away from the combination products that contain pain aids, specifically ibuprofen or nonsteroidal anti-inflammatory (NSAIDs) medications.

More importantly, continue to keep your health care professionals in the loop about your OTC selections. While OTC medications are easily available for self-treatment, it doesn't always mean it is safe and effective for your individual purpose. Read the bottles carefully and ask questions with your pharmacist.