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Effects of Diethylstilbestrol (DES) Exposure - Topic Overview

Between 1948 and 1971, millions of women took a drug called diethylstilbestrol (DES) to prevent miscarriage.

Daughters born to women who took DES while pregnant have a slightly higher risk of developing:

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Adverse Effects

No serious toxicity associated with the use of coenzyme Q10 has been reported. Reviewed in [1,2,3,4]Doses of 100 mg /day or higher have caused mild insomnia in some individuals. Reviewed in [1]Liver enzyme elevation has been detected in patients taking doses of 300 mg/day for extended periods of time, but no liver toxicity has been reported. Reviewed in [1] Researchers in one cardiovascular study reported that coenzyme Q10 caused rashes, nausea, and epigastric (upper abdominal) pain that required...

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  • Abnormal cervical cells that cause an abnormal Pap test result.
  • Cancer of the vagina.
  • Structural problems in the reproductive organs (such as a T-shaped uterus), which can cause infertility.

WebMD Medical Reference from Healthwise

Last Updated: March 12, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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