It is possible that the main title of the report Anemia, Hereditary Spherocytic Hemolytic is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- Acholuric Jaundice
- Chronic Acholuric Jaundice
- Congenital Hemolytic Anemia
- Congenital Hemolytic Jaundice
- Congenital Spherocytic Anemia
- Hereditary Spherocytosis
- Icterus (Chronic Familial)
- Minkowski-Chauffard Syndrome
- Spherocytic Anemia
Hereditary spherocytic hemolytic anemia is a rare blood disorder characterized by defects within red blood cells (intracorpuscular) that result in a shortened survival time for these cells. Red blood cells (erythrocytes) normally circulate for a few months and when they die off is replaced by new erythrocytes. However, in hereditary spherocytic hemolytic anemia, the cells die prematurely. They also have low amounts of fats (lipid) in the cell membranes and an abnormally small amount of surface area. The red blood cells are sphere-shaped (spherocytic) making it difficult for them to pass through the spleen, resulting in the early destruction of these cells (hemolysis). The sphere shape of the red blood cells is the hallmark of this disorder, and this abnormality may be identified under a microscope. Hereditary spherocytic hemolytic anemia is caused by an inherited metabolic defect.
March of Dimes Birth Defects Foundation
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NIH/National Heart, Lung and Blood Institute
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
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Last Updated: 2/20/2007
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