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How can hydroxyurea help with treating pain from sickle cell disease?

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One drug, called hydroxyurea, may keep pain episodes from happening as often for children and adults who take it every day. Scientists are also studying another drug, L-glutamine, to see if it can help people have shorter or fewer hospital visits for sickle cell pain. Ask your doctor if either drug is right for you or your child.

SOURCES:

National Heart, Lung, and Blood Institute: “Sickle Cell Disease.”

CDC: “Sickle Cell Disease - Complications and Treatments.”

Pediatric Blood and Cancer : “Impact of individualized pain plan on the emergency management of children with sickle cell disease.”

Current Opinions in Hematology : “Acute pain in children and adults with sickle cell disease: management in the absence of evidence-based guidelines.”

American Family Physician : “Management of Sickle Cell Disease: Recommendations from the 2014 Expert Panel Report.”

News release, U.S. Food and Drug Administration: “FDA approves hydroxyurea for treatment of pediatric patients with sickle cell anemia.”

Journal of the Royal Society of Medicine: “Management of pain in sickle-cell disease.”

Blood: “Evolution of Chronic Pain in Sickle Cell Disease.”

Child Psychiatry and Human Development: “Symptoms of depression and anxiety in adolescents with sickle cell disease.”

Journal of the National Medical Association : “Health-Related Stigma in Young Adults With Sickle Cell Disease.”

British Journal of Haematologydisease: “Psychological complications in sickle cell .”

Reviewed by Melinda Ratini on March 06, 2018

SOURCES:

National Heart, Lung, and Blood Institute: “Sickle Cell Disease.”

CDC: “Sickle Cell Disease - Complications and Treatments.”

Pediatric Blood and Cancer : “Impact of individualized pain plan on the emergency management of children with sickle cell disease.”

Current Opinions in Hematology : “Acute pain in children and adults with sickle cell disease: management in the absence of evidence-based guidelines.”

American Family Physician : “Management of Sickle Cell Disease: Recommendations from the 2014 Expert Panel Report.”

News release, U.S. Food and Drug Administration: “FDA approves hydroxyurea for treatment of pediatric patients with sickle cell anemia.”

Journal of the Royal Society of Medicine: “Management of pain in sickle-cell disease.”

Blood: “Evolution of Chronic Pain in Sickle Cell Disease.”

Child Psychiatry and Human Development: “Symptoms of depression and anxiety in adolescents with sickle cell disease.”

Journal of the National Medical Association : “Health-Related Stigma in Young Adults With Sickle Cell Disease.”

British Journal of Haematologydisease: “Psychological complications in sickle cell .”

Reviewed by Melinda Ratini on March 06, 2018

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