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What are the side effects of rituximab while treating thrombocytopenia and immune thrombocytopenia (ITP)?

ANSWER

Rituximab is a biologic drug that treats ITP, which causes a blood clotting disorder called thrombocytopenia. Side effects of rituximab include:

  • Fever
  • Chills
  • Weakness
  • Nausea
  • Headaches
  • Weakened immune system

From: Thrombocytopenia and ITP WebMD Medical Reference

SOURCES:

 

Hoffman, R.  , 5th edition, Churchill Livingstone Elsevier, 2009. Hematology: Basic Principles and Practice

 

National Institutes of Health: "How Is Thromobocytopenia Diagnosed?" "Living With Thrombocytopenia."

 

Cleveland Clinic: "Thrombocytopenia."

 

Platelet Disorder Support Association: "Food as a Cure."

 

American Academy of Family Physicians: "Idiopathic Thrombocytopenic Purpura (ITP)."

 

ITP Foundation: "What Is ITP?"

 

UptoDate: "Immune thrombocytopenia (ITP) in adults."

 

FDA: "FDA approves fostamatinib tablets for ITP," April 2018.

 

Medscape: "Rituximab: An anti-CD20 Antibody for the Treatment of Chronic Refractory Immune Thrombocytopenic Purpura."

Reviewed by Arefa Cassoobhoy on November 12, 2018

SOURCES:

 

Hoffman, R.  , 5th edition, Churchill Livingstone Elsevier, 2009. Hematology: Basic Principles and Practice

 

National Institutes of Health: "How Is Thromobocytopenia Diagnosed?" "Living With Thrombocytopenia."

 

Cleveland Clinic: "Thrombocytopenia."

 

Platelet Disorder Support Association: "Food as a Cure."

 

American Academy of Family Physicians: "Idiopathic Thrombocytopenic Purpura (ITP)."

 

ITP Foundation: "What Is ITP?"

 

UptoDate: "Immune thrombocytopenia (ITP) in adults."

 

FDA: "FDA approves fostamatinib tablets for ITP," April 2018.

 

Medscape: "Rituximab: An anti-CD20 Antibody for the Treatment of Chronic Refractory Immune Thrombocytopenic Purpura."

Reviewed by Arefa Cassoobhoy on November 12, 2018

NEXT QUESTION:

What is intravenous immune globulin (IVIG) for treatment of thrombocytopenia?

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