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What causes adenosine deaminase severe combined immunodeficiency (ADA-SCID)?

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This is a serious disease that happens when your body's defenses stop working because of a problem with your genes. You get ADA-SCID only if both your parents pass on a copy of a faulty gene to you. If you get a copy from just one parent, you won't get the disorder, but you can pass that copy on to your own children.

SOURCES:

American Society of Gene & Cell Therapy: ''Gene Therapy for Genetic Disorders.''

Baby’s First Test: ''Severe combined immunodeficiency.''

GeneReviews: ''Adenosine Deaminase Deficiency.''

Great Ormond Street Hospital for Children NHS Trust: "Severe combined immunodeficiency (SCID) information."

Nemours Foundation: ''Severe Combined Immunodeficiency.''

Pai, S. , published online July 31, 2014. New England Journal Of Medicine

NIH: ''Adenosine deaminase deficiency.''

Immune Deficiency Foundation: ''About Primary Immunodeficiency'' and ''Severe Combined Immune Deficiency and Combined Immune Deficiency.''

Reviewed by Dan Brennan on October 16, 2018

SOURCES:

American Society of Gene & Cell Therapy: ''Gene Therapy for Genetic Disorders.''

Baby’s First Test: ''Severe combined immunodeficiency.''

GeneReviews: ''Adenosine Deaminase Deficiency.''

Great Ormond Street Hospital for Children NHS Trust: "Severe combined immunodeficiency (SCID) information."

Nemours Foundation: ''Severe Combined Immunodeficiency.''

Pai, S. , published online July 31, 2014. New England Journal Of Medicine

NIH: ''Adenosine deaminase deficiency.''

Immune Deficiency Foundation: ''About Primary Immunodeficiency'' and ''Severe Combined Immune Deficiency and Combined Immune Deficiency.''

Reviewed by Dan Brennan on October 16, 2018

NEXT QUESTION:

What are symptoms of adenosine deaminase severe combined immunodeficiency (ADA-SCID)?

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