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What causes myelodysplastic syndromes (MDS)?

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Some people are born with a gene that causes MDS. These genes are usually passed down from one or both parents. If you have certain inherited syndromes, including Fanconi anemia, Shwachman-Diamond syndrome, Diamond Blackfan anemia, familial platelet disorder, and severe congenital neutropenia, you could be more likely to develop MDS.

A small number of people also get MDS after radiation or chemotherapy treatment for cancer. Another risk is exposure to chemicals like benzene, which is found in tobacco smoke.

From: Rare Types of Anemia WebMD Medical Reference

Reviewed by Louise Chang on September 15, 2018

Medically Reviewed on 09/15/2018

SOURCES:

American Cancer Society: "What are Myelodysplastic Syndromes?"

American Society for Clinical Oncology: "Myelodysplastic Syndromes -- MDS -- Symptoms and Signs." "Myelodysplastic Syndromes -- MDS -- Treatment Options."

American Society of Hematology: "Anemia."

Cincinnati Children's Hospital: "Fanconi Anemia."

Dana-Farber Cancer and Blood Disorders Center: "Congenital Dyserythropoietic Anemia Overview."

Leukemia & Lymphoma Society: "Myelodysplastic Syndromes."

National Center for Advancing Translational Sciences: "Sideroblastic anemia."

National Heart, Lung, and Blood Institute: "How is Aplastic Anemia Treated?" "What Are the Signs and Symptoms of Aplastic Anemia?" "What Causes Aplastic Anemia?"

National Organization for Rare Disorders: "Anemia, Blackfan Diamond." "Anemia, Hemolytic, Acquired Autoimmune." "Anemia, Megaloblastic." "Anemias, Sideroblastic." "Fanconi Anemia."

Seattle Children's Hospital: "Diamond Blackfan Anemia Symptoms and Diagnosis."

Reviewed by Louise Chang on September 15, 2018

SOURCES:

American Cancer Society: "What are Myelodysplastic Syndromes?"

American Society for Clinical Oncology: "Myelodysplastic Syndromes -- MDS -- Symptoms and Signs." "Myelodysplastic Syndromes -- MDS -- Treatment Options."

American Society of Hematology: "Anemia."

Cincinnati Children's Hospital: "Fanconi Anemia."

Dana-Farber Cancer and Blood Disorders Center: "Congenital Dyserythropoietic Anemia Overview."

Leukemia & Lymphoma Society: "Myelodysplastic Syndromes."

National Center for Advancing Translational Sciences: "Sideroblastic anemia."

National Heart, Lung, and Blood Institute: "How is Aplastic Anemia Treated?" "What Are the Signs and Symptoms of Aplastic Anemia?" "What Causes Aplastic Anemia?"

National Organization for Rare Disorders: "Anemia, Blackfan Diamond." "Anemia, Hemolytic, Acquired Autoimmune." "Anemia, Megaloblastic." "Anemias, Sideroblastic." "Fanconi Anemia."

Seattle Children's Hospital: "Diamond Blackfan Anemia Symptoms and Diagnosis."

Reviewed by Louise Chang on September 15, 2018

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What are the symptoms of myelodysplastic syndromes (MDS)?

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