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What causes porphyria cutanea tarda?

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Although the enzyme deficiency that causes porphyria cutanea tarda (PCT) can be inherited, most people who inherit it never show symptoms. Instead, the disease becomes active when the deficiency is triggered by certain conditions or lifestyle choices. These include:

  • Drinking alcohol
  • Estrogen use in females
  • Hepatitis C
  • HIV
  • Smoking

From: Porphyria WebMD Medical Reference

SOURCES:

National Human Genome Research Institute: "Learning about Porphyria."

NIH Rare Diseases Clinical Research Network: "Porphyria Overview," "Treatment and Prevention," "Acute Intermittent Porphyria," "Frequently Asked Questions"

American Porphyria Foundation: "Porphyria Cutanea Tarda," "Congenital Erythropoietic Porphyria (CEP)," "Variegate Porphyria (VP)," "Hepatoerythropoietic Porphyria (HEP)," "ALAD-Deficiency Porphyria (ADP)," "About Porphyria."

Genetic and Rare Diseases Information Center: "Porphyria Cutanea Tarda."

Reviewed by Melinda Ratini on August 16, 2017

SOURCES:

National Human Genome Research Institute: "Learning about Porphyria."

NIH Rare Diseases Clinical Research Network: "Porphyria Overview," "Treatment and Prevention," "Acute Intermittent Porphyria," "Frequently Asked Questions"

American Porphyria Foundation: "Porphyria Cutanea Tarda," "Congenital Erythropoietic Porphyria (CEP)," "Variegate Porphyria (VP)," "Hepatoerythropoietic Porphyria (HEP)," "ALAD-Deficiency Porphyria (ADP)," "About Porphyria."

Genetic and Rare Diseases Information Center: "Porphyria Cutanea Tarda."

Reviewed by Melinda Ratini on August 16, 2017

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How are acute porphyria and porphyria cutanea tarda treated?

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