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What causes sideroblastic anemia?

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In this group of blood disorders, your body can't use iron to make hemoglobin -- the protein that carries oxygen in your blood. Iron builds up and forms abnormal red blood cells called sideroblasts.

Acquired sideroblastic anemia is caused by exposure to certain chemicals or drugs.

Hereditary sideroblastic anemia happens when a gene mutates and disrupts normal hemoglobin production. This gene produces “heme,” the part of hemoglobin that carries oxygen.

From: Rare Types of Anemia WebMD Medical Reference

Reviewed by Louise Chang on September 15, 2018

Medically Reviewed on 09/15/2018

SOURCES:

American Cancer Society: "What are Myelodysplastic Syndromes?"

American Society for Clinical Oncology: "Myelodysplastic Syndromes -- MDS -- Symptoms and Signs." "Myelodysplastic Syndromes -- MDS -- Treatment Options."

American Society of Hematology: "Anemia."

Cincinnati Children's Hospital: "Fanconi Anemia."

Dana-Farber Cancer and Blood Disorders Center: "Congenital Dyserythropoietic Anemia Overview."

Leukemia & Lymphoma Society: "Myelodysplastic Syndromes."

National Center for Advancing Translational Sciences: "Sideroblastic anemia."

National Heart, Lung, and Blood Institute: "How is Aplastic Anemia Treated?" "What Are the Signs and Symptoms of Aplastic Anemia?" "What Causes Aplastic Anemia?"

National Organization for Rare Disorders: "Anemia, Blackfan Diamond." "Anemia, Hemolytic, Acquired Autoimmune." "Anemia, Megaloblastic." "Anemias, Sideroblastic." "Fanconi Anemia."

Seattle Children's Hospital: "Diamond Blackfan Anemia Symptoms and Diagnosis."

Reviewed by Louise Chang on September 15, 2018

SOURCES:

American Cancer Society: "What are Myelodysplastic Syndromes?"

American Society for Clinical Oncology: "Myelodysplastic Syndromes -- MDS -- Symptoms and Signs." "Myelodysplastic Syndromes -- MDS -- Treatment Options."

American Society of Hematology: "Anemia."

Cincinnati Children's Hospital: "Fanconi Anemia."

Dana-Farber Cancer and Blood Disorders Center: "Congenital Dyserythropoietic Anemia Overview."

Leukemia & Lymphoma Society: "Myelodysplastic Syndromes."

National Center for Advancing Translational Sciences: "Sideroblastic anemia."

National Heart, Lung, and Blood Institute: "How is Aplastic Anemia Treated?" "What Are the Signs and Symptoms of Aplastic Anemia?" "What Causes Aplastic Anemia?"

National Organization for Rare Disorders: "Anemia, Blackfan Diamond." "Anemia, Hemolytic, Acquired Autoimmune." "Anemia, Megaloblastic." "Anemias, Sideroblastic." "Fanconi Anemia."

Seattle Children's Hospital: "Diamond Blackfan Anemia Symptoms and Diagnosis."

Reviewed by Louise Chang on September 15, 2018

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What are the symptoms of sideroblastic anemia?

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