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What drugs are more likely to cause an allergic reaction?

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Any medication can trigger an allergic reaction, but some are more likely to cause problems than others:

  • Antibiotics
  • Nonsteroidal anti-inflammatory drugs like ibuprofen and naproxen
  • Aspirin
  • Sulfa drugs
  • Chemotherapy drugs
  • Monoclonal antibody therapy -- cetuximab, rituximab, and others
  • HIV drugs -- abacavir, nevirapine, and others
  • Insulin
  • Antiseizure drugs
  • Muscle relaxers given by IV -- atracurium, succinylcholine, or vecuronium

From: Common Drugs That Cause Allergies WebMD Medical Reference

SOURCES:

American Academy of Allergy, Asthma, and Immunology: "Drug Allergy," "Medications and Drug Allergic Reactions: Tips to Remember," "Anaphylaxis: Tips to Remember."

American College of Allergy, Asthma & Immunology: "Drug Reactions and Drug Allergies."

CDC:  "Who Should NOT Get Vaccinated with these Vaccines?"

Medscape: "Anaphylaxis."

Solensky R. Immunology, October, 2010. Annals of Allergy, Asthma &

UpToDate: "An approach to the patient with drug allergy," "Comparison of systemic immunologic drug reactions."

World Allergy Organization: "Allergy to Anesthetic Agents." 

Reviewed by Jennifer Robinson on December 16, 2018

SOURCES:

American Academy of Allergy, Asthma, and Immunology: "Drug Allergy," "Medications and Drug Allergic Reactions: Tips to Remember," "Anaphylaxis: Tips to Remember."

American College of Allergy, Asthma & Immunology: "Drug Reactions and Drug Allergies."

CDC:  "Who Should NOT Get Vaccinated with these Vaccines?"

Medscape: "Anaphylaxis."

Solensky R. Immunology, October, 2010. Annals of Allergy, Asthma &

UpToDate: "An approach to the patient with drug allergy," "Comparison of systemic immunologic drug reactions."

World Allergy Organization: "Allergy to Anesthetic Agents." 

Reviewed by Jennifer Robinson on December 16, 2018

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What can raise your chance of an allergic reactions to common drugs?

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