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What is an immune complex assay and does it help diagnose food allergies?

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People who may have food allergies sometimes get an immune complex assay to see if complexes of certain antibodies bind to the food allergen in the bloodstream. The idea is that these immune complexes correlate with food allergies. But the formation of such immune complexes is a normal offshoot of food digestion, and everyone, if tested with a sensitive enough measurement, has them. No research conclusively shows that this test correlates with allergies to foods.

SOURCES:

The National Institute of Allergy and Infectious Diseases: "Fact Sheet: Food Allergy and Intolerances."  UpToDate. American Academy of Allergy Asthma & Immunology.

Reviewed by Melinda Ratini on February 18, 2020

SOURCES:

The National Institute of Allergy and Infectious Diseases: "Fact Sheet: Food Allergy and Intolerances."  UpToDate. American Academy of Allergy Asthma & Immunology.

Reviewed by Melinda Ratini on February 18, 2020

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What is an IgG assay and does it diagnose food allergies?

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