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How can insulin resistance cause Alzheimer's disease?

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When your cells don't use insulin the way they should, that affects the mechanics of your brain.

These effects on the brain are so strong that some scientists feel that Alzheimer's related to insulin resistance should be called "type 3 diabetes."

  • Your cells don't get the fuel they need, so your brain can't work right.
  • Your blood sugar goes up, and over time, that can cause harmful fatty deposits in your blood vessels.
  • Too much insulin can throw off the balance of chemicals in your brain.

SOURCES:

American Diabetes Association: "Aerobic Exercise Improves Brain Function for People with Prediabetes," "Types of Activity: What We Recommend."

"Diabetes and Cognitive Decline," Alzheimer's Association, October 2015.

National Institute of Diabetes and Digestive and Kidney Diseases: "Diabetes, Heart Disease, and Stroke."

"Alzheimer's Disease and Type 2 Diabetes: A Growing Connection," Alzheimer's Association, 2007.

De la Monte, S.M. November 2008. Journal of Diabetes Science and Technology,

Harvard Health Publications: "What you eat can fuel or cool inflammation, a key driver of heart disease, diabetes, and other chronic conditions."

Chen, L. published online June 2, 2015. International Journal of Endocrinology,

Alzheimer's Association: "Brain Tour," "Brain Health: Stay Physically Active."

American Academy of Neurology: "Diabetes and Brain Tangles May Be Linked Independently of Alzheimer's Disease."

Kawamura, T. published online Aug. 29, 2012. Journal of Diabetes Investigation,

Reviewed by Neil Lava on August 04, 2018

SOURCES:

American Diabetes Association: "Aerobic Exercise Improves Brain Function for People with Prediabetes," "Types of Activity: What We Recommend."

"Diabetes and Cognitive Decline," Alzheimer's Association, October 2015.

National Institute of Diabetes and Digestive and Kidney Diseases: "Diabetes, Heart Disease, and Stroke."

"Alzheimer's Disease and Type 2 Diabetes: A Growing Connection," Alzheimer's Association, 2007.

De la Monte, S.M. November 2008. Journal of Diabetes Science and Technology,

Harvard Health Publications: "What you eat can fuel or cool inflammation, a key driver of heart disease, diabetes, and other chronic conditions."

Chen, L. published online June 2, 2015. International Journal of Endocrinology,

Alzheimer's Association: "Brain Tour," "Brain Health: Stay Physically Active."

American Academy of Neurology: "Diabetes and Brain Tangles May Be Linked Independently of Alzheimer's Disease."

Kawamura, T. published online Aug. 29, 2012. Journal of Diabetes Investigation,

Reviewed by Neil Lava on August 04, 2018

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How can diabetes make you more likely to get Alzheimer's disease?

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