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How does Pick's disease develop?

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Your brain uses a transport system to help move around the nutrients it needs. This system is made of proteins that guide nutrients where they need to go. The proteins are called tau proteins.

When you have Pick's disease, the tau proteins don't work the way they should. You may also have more of them in your brain than other people.

These abnormal clumps of tau proteins are called Pick bodies. Pick bodies "derail" your transport system. Nutrients in the brain can't get where they need to go. This causes brain damage that can't be reversed.

From: What Is Pick's Disease? WebMD Medical Reference

SOURCES:

Alzheimer's Association: "Brain Tour," "Frontotemporal Dementia (FTD)."

The Association for Frontotemporal Degeneration: "Pick's Disease."

National Institute of Neurological Disorders and Stroke: "Frontotemporal Dementia." 

National Organization for Rare Disorders: "Frontotemporal Degeneration."

Medscape: "Pick Disease."

Reviewed by Jennifer Robinson on November 15, 2018

SOURCES:

Alzheimer's Association: "Brain Tour," "Frontotemporal Dementia (FTD)."

The Association for Frontotemporal Degeneration: "Pick's Disease."

National Institute of Neurological Disorders and Stroke: "Frontotemporal Dementia." 

National Organization for Rare Disorders: "Frontotemporal Degeneration."

Medscape: "Pick Disease."

Reviewed by Jennifer Robinson on November 15, 2018

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How many people in the United States have Pick's disease?

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