If you’re anything like me, those first few months after starting a new medication can feel like a whirlwind of emotions. You’re hopeful, yet nervous, and sometimes even a little impatient. When your rheumatologist prescribed a biologic to help control your ankylosing spondylitis pain, you probably thought, “I hope this works!”
But now, 3 months have passed, and you might be wondering, "Is this working?" If you're not feeling a big difference, it can be hard to tell.
Over the last 20 years, I’ve been on five different biologics to control my AS. I’ll walk you through some ways you can determine if your biologic is working.
Reduced Pain and Stiffness
One of the first things I noticed when taking my biologic was that my pain wasn’t as intense. I used to wake up every morning feeling like my knees were on fire. But over time, the pain started to ease.
If your biologic is working, you might find your pain and stiffness aren’t as severe. Especially in the morning when AS symptoms are often at their worst.
Take a moment to think back to how you felt before starting your biologic. Are there certain movements that don't hurt as much now? Or maybe you're not as stiff when you wake up. These small changes might be a sign that your medication is beginning to help.
Better Sleep Quality
We all know how important sleep is. When you’re in pain, getting a good night’s sleep can feel impossible. I remember tossing and turning, trying to find a position that didn’t hurt. As my biologic started to work, I found that I could sleep more soundly.
If you’re sleeping better these days, your biologic may be working. Maybe you’re waking up less often during the night, or you’re not feeling as achy when you lie down.
A good night’s sleep can make a huge difference in how you feel overall. If your sleep is improving, that’s a win!
Decreased Need for Other Pain Medications
Before starting my biologic, I was reaching for pain relief more often than I’d like to admit. Over-the-counter meds, heating pads – you name it, I tried it. But once my biologic started to kick in, I found I didn’t need those other pain relievers as much.
If you’re finding you don’t need to rely on extra pain medications as often, this is a good sign. This doesn’t mean you’ll never need them again. However, if you’re noticing a decrease in how often you’re reaching for your bottle of pain relievers, this is encouraging.
Improved Mobility
One of the toughest things about AS is how your mobility can be limited. Bending over to tie your shoes or reaching for something on a high shelf can feel like a monumental effort. You might notice you’re able to move more easily as your biologic starts to kick in.
Are you finding things easier to do that used to be tough? Are you able to walk a little farther? Improved mobility is a big indicator your biologic is helping to control your symptoms.
Less Swelling and Tenderness
AS can cause pain, stiffness, and lead to tenderness in your joints. For me, the swelling in my knees was a constant reminder of my condition. As the biologic started to take effect, I noticed the swelling began to go down.
Reduced inflammation is ideal because this means your body is responding well to the medication.
A More Positive Mood
Pain can take a toll on your mental health. When you’re hurting all the time, you can feel down or frustrated. I know I did. When my biologic started to work, I noticed my mood improved. I felt more positive and hopeful. I wasn’t as weighed down by the daily struggles of living with AS.
Having doubts about whether your biologic is working is normal, especially if the changes are subtle. But even small improvements can add up over time.
Keep track of how you’re feeling, and don’t hesitate to talk to your rheumatologist at your follow-up visit. They can help you determine if the medication is working or if adjustments need to be made.
Everyone’s journey with AS is different, and finding the right treatment can take time. Be patient with yourself. Celebrate the progress you’re making, no matter how small.
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