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What headache or migraine medicines have caffeine in them?

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Some headache and migraine medicines include caffeine. It’s a drug that stimulates your nervous system, which can rev up your heart and blood pressure and make you jittery, nervous, and anxious. If you’re prone to anxiety, caffeine can heighten your symptoms.

You might have issues if you’re taking these meds for headache or migraine:

  • Aspirin, acetaminophen, and caffeine (Excedrin Migraine)
  • Aspirin and caffeine (Anacin)
  • Ergotamine and caffeine (Migergot, Cafergot), also called ergots, which treat migraines

From: What Meds Might Cause Anxiety? WebMD Medical Reference

SOURCES:

Advances in Psychiatric Treatment : “Neuropsychiatric effects of caffeine.”

Cochrane Database System Review : “Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures.”

FDA: “Medicines in my Home: Caffeine and Your Body.”

International Journal of Child Health and Human Development: “Asthma and Mood Disorders.”

Journal of Pharmacology and Pharmacotherapeutics : “Corticosteroid-related central nervous system side effects.”

Mayo Clinic: “Anxiety,” “Migraine,” “Prednisone and other corticosteroids.”

Parkinson’s Disease Foundation: “Prescription Medications.”

Psychiatry (Edgmont) : “Real-World Data on Attention Deficit Hyperactivity Disorder Medication Side Effects.”

UpToDate: “Theophylline use in asthma.”

U.S. National Library of Medicine: “Albuterol (oral route),” “Salmeterol (Inhalation route),” “Thyroid,” “Phenytoin.”

Reviewed by Smitha Bhandari on June 20, 2017

SOURCES:

Advances in Psychiatric Treatment : “Neuropsychiatric effects of caffeine.”

Cochrane Database System Review : “Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures.”

FDA: “Medicines in my Home: Caffeine and Your Body.”

International Journal of Child Health and Human Development: “Asthma and Mood Disorders.”

Journal of Pharmacology and Pharmacotherapeutics : “Corticosteroid-related central nervous system side effects.”

Mayo Clinic: “Anxiety,” “Migraine,” “Prednisone and other corticosteroids.”

Parkinson’s Disease Foundation: “Prescription Medications.”

Psychiatry (Edgmont) : “Real-World Data on Attention Deficit Hyperactivity Disorder Medication Side Effects.”

UpToDate: “Theophylline use in asthma.”

U.S. National Library of Medicine: “Albuterol (oral route),” “Salmeterol (Inhalation route),” “Thyroid,” “Phenytoin.”

Reviewed by Smitha Bhandari on June 20, 2017

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Can medications with caffeine cause anxiety?

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THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

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