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How do prednisone and systemic steroids work to increase asthma control?

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Using systemic steroids (steroids taken by mouth or by injection that can affect the entire body) such as prednisone , prednisolone, and methylprednisolone helps to treat severe asthma episodes, allowing people to gain better asthma control. Prednisone and other steroid drugs may be used to help control sudden and severe asthma attacks or in rare cases to treat long-term, hard-to-control asthma.

Most often, prednisone or another steroid is taken in high doses for a few days (called a steroid burst) for more severe asthma attacks.

Side effects of systemic steroids can include weakness, acne, weight gain, mood or behavior changes, upset stomach, bone loss, eye changes, and slowing of growth. These side effects rarely occur with short-term use, such as for an acute asthma attack.

SOURCES:

American Academy of Allergy, Asthma & Immunology: "Asthma Medications."

American Lung Association: "Long-Term Control Medications."

Asthma and Allergy Foundation of America: "Non-Allergic Asthma."

Boehringer Ingelheim: "US FDA Expands Approval of Tiotropium Respimat® for Maintenance Treatment of Asthma in Children."

FDA News Release. “FDA approves Cinqair to treat severe asthma.”

FDA. Prescribing Information: Spiriva Respimat.

News release, Merck.

News release, GlaxoSmithKline.

NIH, MedlinePlus: "Omalizumab Injection."

 

Reviewed by Carol DerSarkissian on August 11, 2019

SOURCES:

American Academy of Allergy, Asthma & Immunology: "Asthma Medications."

American Lung Association: "Long-Term Control Medications."

Asthma and Allergy Foundation of America: "Non-Allergic Asthma."

Boehringer Ingelheim: "US FDA Expands Approval of Tiotropium Respimat® for Maintenance Treatment of Asthma in Children."

FDA News Release. “FDA approves Cinqair to treat severe asthma.”

FDA. Prescribing Information: Spiriva Respimat.

News release, Merck.

News release, GlaxoSmithKline.

NIH, MedlinePlus: "Omalizumab Injection."

 

Reviewed by Carol DerSarkissian on August 11, 2019

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How do the leukotriene modifiers improve asthma control?

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