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What are the odds of getting an abnormal quad marker screen result?

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Out of 1,000 pregnant women, approximately 50 will have quad marker screen results that indicate an increased risk for having a baby with a birth defect. Of those 50 women, only one or two will actually have a baby with an open neural tube defect. About 40 women will have quad marker screen results that show an increased risk for having a baby with Down syndrome and one or two will actually have a baby with Down syndrome.

From: Pregnancy and the Quad Marker Screen WebMD Medical Reference

Reviewed by Trina Pagano on September 19, 2016

Medically Reviewed on 09/19/2016

SOURCES: The March of Dimes.  , "Second trimester maternal serum screening for fetal open neural tube defects and aneuploidy." American College of Medical Genetics, 2004.


Deborah A. Driscoll, MD

Reviewed by Trina Pagano on September 19, 2016

SOURCES: The March of Dimes.  , "Second trimester maternal serum screening for fetal open neural tube defects and aneuploidy." American College of Medical Genetics, 2004.


Deborah A. Driscoll, MD

Reviewed by Trina Pagano on September 19, 2016

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Who should have the quad marker screen?

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