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Are antidepressants used to treat bipolar depression?

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While antidepressants are effective treatment for people with major depressive (unipolar) disorder, they're not always as effective for bipolar depression, and generally shouldn't be given alone (monotherapy) in people with bipolar I disorder. When antidepressants are given alone to someone with bipolar disorder, there's a risk the drug might trigger a manic episode in some patients.

From: Treating Bipolar Depression WebMD Medical Reference

SOURCES:

National Institute of Mental Health: Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).

American Psychiatric Association: "2002 Practice Guidelines."

Sunovion Pharmaceuticals Inc.

Reviewed by Joseph Goldberg on October 13, 2017

SOURCES:

National Institute of Mental Health: Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).

American Psychiatric Association: "2002 Practice Guidelines."

Sunovion Pharmaceuticals Inc.

Reviewed by Joseph Goldberg on October 13, 2017

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How do the CNS depressants help with bipolar disorder depression?

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