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Can I drink grapefruit juice while on bipolar drugs?

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Talk to your doctor or pharmacist about eating grapefruit or drinking grapefruit juice with your bipolar medication. Grapefruit juice may increase the blood levels of many psychiatric medications that are used in bipolar disorder. These include some antidepressants (such as Zoloft or Luvox), the anti-anxiety drug Buspar, certain anticonvulsants (such as Tegretol), some antipsychotics (such as Latuda, Seroquel or Geodon), stimulants (such as Adderall, Adderall XR, or Dexedrine), and many sedative-hypnotics (benzodiazepines), such as Klonopin, Xanax, Valium, and Ativan, which could cause excessive drowsiness, mental impairment and even toxicity.

SOURCES:

American Psychiatric Association: "Treatment of Patients with Bipolar Disorder."

Depression and Bipolar Support Alliance: "What You Need to Know About Dietary Supplements."

Depression and Bipolar Support Alliance: "Depression and Other Illnesses."

Reviewed by Smitha Bhandari on May 9, 2017

SOURCES:

American Psychiatric Association: "Treatment of Patients with Bipolar Disorder."

Depression and Bipolar Support Alliance: "What You Need to Know About Dietary Supplements."

Depression and Bipolar Support Alliance: "Depression and Other Illnesses."

Reviewed by Smitha Bhandari on May 9, 2017

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Should you take bipolar medication with or without food?

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