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Do selective serotonin reuptake inhibitor (SSRI) antidepressants work for bipolar disorder?

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Traditional antidepressants are considered experimental therapy for bipolar depression. That’s because they have not been proven to work any better than placebo, or dummy, pills. Still, your doctor may have you take SSRIs, which are newer class of antidepressants, along with lithium or other mood stabilizing drugs for your bipolar depression. Researchers think that if SSRIs help, they work by boosting the workings of nerve cells in the brain that communicate through the chemical serotonin.

SOURCES: WebMD Medical Reference: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment. National Institute for Mental Health: "Step-BD Womens Studies."   Massachusetts General Hospital Bipolar Clinic & Research Program. MedicineNet.com: "Bipolar Disorder (Mania)." WebMD Medical Reference: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."






Reviewed by Smitha Bhandari on June 4, 2017

SOURCES: WebMD Medical Reference: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment. National Institute for Mental Health: "Step-BD Womens Studies."   Massachusetts General Hospital Bipolar Clinic & Research Program. MedicineNet.com: "Bipolar Disorder (Mania)." WebMD Medical Reference: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."






Reviewed by Smitha Bhandari on June 4, 2017

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What are some selective serotonin reuptake inhibitor (SSRI) antidepressants?

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