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How do calcium channel blockers work?

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These drugs are usually used to treat high blood pressure or heart problems. They block the small pores in cells that let calcium pass through, and widen blood vessels as well as affect the activity of nerve cells. Research suggests that the way the brain uses calcium to regulate nerve cells may not work right in some people with bipolar disorder. So calcium channel blockers have been studied as a treatment for bipolar disorder, but there isn’t enough evidence yet that they work.

SOURCES: WebMD Medical Reference: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment. National Institute for Mental Health: "Step-BD Womens Studies."   Massachusetts General Hospital Bipolar Clinic & Research Program. MedicineNet.com: "Bipolar Disorder (Mania)." WebMD Medical Reference: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."






Reviewed by Joseph Goldberg on October 16, 2018

SOURCES: WebMD Medical Reference: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment. National Institute for Mental Health: "Step-BD Womens Studies."   Massachusetts General Hospital Bipolar Clinic & Research Program. MedicineNet.com: "Bipolar Disorder (Mania)." WebMD Medical Reference: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."






Reviewed by Joseph Goldberg on October 16, 2018

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Which calcium channel blockers have been studied to treat bipolar disorder?

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