PREVIOUS QUESTION:

 

NEXT QUESTION:

 

How do tricyclic antidepressants work in treating bipolar disorder?

ANSWER

These drugs help activate the brain chemicals serotonin and norepinephrine, which may play a role in regulating mood. But tricyclic antidepressants also may raise your chances of mania or rapid cycling, as well as certain kinds of heart rhythm problems. They also can be deadly if you overdose. These drugs aren’t prescribed as often these days for bipolar disorder.

SOURCES: WebMD Medical Reference with The Cleveland Clinic: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment. National Institute for Mental Health: "Step-BD Womens Studies." Massachusetts General Hospital Bipolar Clinic & Research Program. MedicineNet.com: "Bipolar Disorder (Mania)." WebMD Medical Reference with The Cleveland Clinic: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."

Reviewed by Joseph Goldberg on October 16, 2018

SOURCES: WebMD Medical Reference with The Cleveland Clinic: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment. National Institute for Mental Health: "Step-BD Womens Studies." Massachusetts General Hospital Bipolar Clinic & Research Program. MedicineNet.com: "Bipolar Disorder (Mania)." WebMD Medical Reference with The Cleveland Clinic: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."

Reviewed by Joseph Goldberg on October 16, 2018

NEXT QUESTION:

What are monoamine oxidase inhibitors (MAOIs)?

WAS THIS ANSWER HELPFUL

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

    This tool does not provide medical advice. See additional information.

    Other Answers On: