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How quickly will SSRI antidepressants for bipolar disorder work?

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Most SSRI antidepressants prescribed for bipolar depression take several weeks to start working. Though the first one that is prescribed works in the majority of people, others may need to try 2 or 3 to find the right one. Your doctor may also prescribe a sedative to help relieve anxiety, agitation, or sleep problems while the antidepressant begins to work.

SOURCES: WebMD Medical Reference: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment. National Institute for Mental Health: "Step-BD Womens Studies."   Massachusetts General Hospital Bipolar Clinic & Research Program. MedicineNet.com: "Bipolar Disorder (Mania)." WebMD Medical Reference: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."






Reviewed by Smitha Bhandari on June 04, 2017

SOURCES: WebMD Medical Reference: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment. National Institute for Mental Health: "Step-BD Womens Studies."   Massachusetts General Hospital Bipolar Clinic & Research Program. MedicineNet.com: "Bipolar Disorder (Mania)." WebMD Medical Reference: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."






Reviewed by Smitha Bhandari on June 04, 2017

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What are side effects of selective serotonin reuptake inhibitor (SSRI) antidepressants for bipolar depression?

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