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What drugs are used to treat restless legs syndrome (RLS)?

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Drugs used to treat restless legs syndrome (RLS) include:

  • Dopaminergic drugs, which act on the neurotransmitter dopamine in the brain. Mirapex, Neupro, and Requip are FDA-approved for treatment of moderate to severe RLS. Others, such as levodopa, may also be prescribed.
  • Benzodiazepines, a class of sedative medications, may be used to help with sleep, but they can cause daytime drowsiness.
  • Narcotic pain relievers may be used for severe pain.
  • Anticonvulsants, or antiseizure drugs, such as Tegretol, Lyrica, Neurontin, and Horizant.

From: Restless Legs Syndrome WebMD Medical Reference

SOURCES:

News release, FDA.

The University of Washington Neuroscience for Kids: "Restless Legs Syndrome."

National Institute of Neurological Disorders and Stroke: "Restless Legs Syndrome Fact Sheet."

Restless Legs Syndrome Foundation: "About RLS: Frequently Asked Questions."

Reviewed by Minesh Khatri on April 30, 2017

SOURCES:

News release, FDA.

The University of Washington Neuroscience for Kids: "Restless Legs Syndrome."

National Institute of Neurological Disorders and Stroke: "Restless Legs Syndrome Fact Sheet."

Restless Legs Syndrome Foundation: "About RLS: Frequently Asked Questions."

Reviewed by Minesh Khatri on April 30, 2017

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Is there a cure for restless legs syndrome (RLS)?

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