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What other medical conditions have been linked to restless legs syndrome (RLS)?

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Other medical conditions linked to restless legs syndrome (RLS) include:

a. Alcohol

b. Caffeine

c. Anticonvulsant drugs (such as Dilantin)

d. Antidepressant drugs (including amitriptyline, Paxil)

e. Beta-blockers (drugs often used to treat high blood pressure)

f. Antipsychotics

  • Parkinson's disease
  • Varicose veins
  • Some tumors
  • Fibromyalgia
  • Hyper- or hypothyroidism (over- or underactive thyroid glands)
  • Pregnancy
  • Cigarette smoking
  • Vitamin and mineral deficiency, such as magnesium deficiency and vitamin B-12 deficiency
  • Severe kidney disease and uremia (kidney failure causing build up of toxins within the body)
  • Amyloidosis (build-up of a starch-like substance in the body's tissues and organs)
  • Lyme disease
  • Damage to spinal nerves
  • Rheumatoid arthritis and Sjögren syndrome
  • Certain medications or substances, such as:
  • g. Withdrawal from certain drugs, such as vasodilator drugs (for example, Apresoline), sedatives, or antidepressants (for example, Tofranil)

SOURCE: eMedicine Health.

Reviewed by Neil Lava on May 05, 2019

SOURCE: eMedicine Health.

Reviewed by Neil Lava on May 05, 2019

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What are the risk factors for restless legs syndrome (RLS)?

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