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How is invasive lobular carcinoma (ILC) treated?

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Most women with invasive lobular carcinoma (ILC) have surgery to remove the cancer from the breast. In most cases, the cancer can be taken out without removing the entire breast. It will depend on the size of your tumor and how much it has spread throughout your breast and surrounding lymph nodes.

Your doctor may also recommend treating it with chemotherapy, radiation therapy, hormone therapy, or some combination of the three. Chemotherapy and hormone therapy are systemic treatments. They target cancer cells throughout your entire body. Radiation specifically focuses on the area around your breast cancer. Cells in invasive lobular carcinoma often contain estrogen and progesterone receptors. There are hormone treatments to specifically target these cells.

Other targeted therapies may help if the cancer is HER2-positive.

SOURCES:

Breastcancer.org: “Lobular carcinoma in situ;” “Invasive lobular carcinoma;” ”Bone Scans;” “LCIS and Breast Cancer Risk;” ”Treatments for LCIS;” “Test for Diagnosing ILC;” and “Systemic Treatments for ILC: Chemotherapy, Hormonal Therapy, Targeted Therapies.”

Breast Cancer Network of Strength: “Lobular carcinoma in situ” and “Infiltrating lobular carcinoma.”

National Cancer Institute: “Lobular carcinoma in situ.”

American Cancer Society: “What is breast cancer?” and "Special Section: Breast Carcinoma in Situ."

College of American Pathologists: “Lobular carcinoma in situ“ and "Invasive lobular carcinoma.”

MedlinePlus: “Tamoxifen.”

Reviewed by Laura J. Martin on March 17, 2019

SOURCES:

Breastcancer.org: “Lobular carcinoma in situ;” “Invasive lobular carcinoma;” ”Bone Scans;” “LCIS and Breast Cancer Risk;” ”Treatments for LCIS;” “Test for Diagnosing ILC;” and “Systemic Treatments for ILC: Chemotherapy, Hormonal Therapy, Targeted Therapies.”

Breast Cancer Network of Strength: “Lobular carcinoma in situ” and “Infiltrating lobular carcinoma.”

National Cancer Institute: “Lobular carcinoma in situ.”

American Cancer Society: “What is breast cancer?” and "Special Section: Breast Carcinoma in Situ."

College of American Pathologists: “Lobular carcinoma in situ“ and "Invasive lobular carcinoma.”

MedlinePlus: “Tamoxifen.”

Reviewed by Laura J. Martin on March 17, 2019

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