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What is the Oncotype DX test for breast cancer?

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Oncotype DX is a test that may be able to tell if your breast cancer is likely to come back. It can help your doctor pick the best treatment from the start, including whether you should have chemotherapy. This test uses tissue taken during your earlier biopsy or surgery. It measures the breast cancer genes. (You might hear it called a "21-gene signature.") Your doctor might suggest the test if you have:

You may also have it you’ve recently been diagnosed with ductal carcinoma in situ (DCIS). It can help in deciding to have radiation treatments.

  • Stage I or II invasive breast cancer
  • Estrogen-receptor positive (called ER+) cancer, meaning the disease's cells grow in response to the hormone estrogen
  • Cancer that isn’t in the lymph nodes

SOURCES:

American Cancer Society: "How Is Breast Cancer Diagnosed?"

Breastcancer.org: "Oncotype DX Test."

National Cancer Institute: "Tumor Markers."

MedlinePlus: “Tamoxifen.”

Reviewed by Laura J. Martin on December 10, 2019

SOURCES:

American Cancer Society: "How Is Breast Cancer Diagnosed?"

Breastcancer.org: "Oncotype DX Test."

National Cancer Institute: "Tumor Markers."

MedlinePlus: “Tamoxifen.”

Reviewed by Laura J. Martin on December 10, 2019

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What do scores mean in an Oncotype DX test for breast cancer?

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