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What is high-grade squamous intraepithelial lesion (LGSIL) in the cervix?

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High-grade squamous intraepithelial lesion (HGSIL) is a type of precancerous changes in the cervix. This is when you have a lot of precancerous cells, which look very different from normal cells. These changes involve only cells on the surface of the cervix. They happen most often in women ages 30 to 40 years, but can happen at any age.

Precancerous cells, even high-grade lesions, usually do not turn cancerous and invade deeper layers of the cervix for many months, perhaps years.

SOURCE: 

 

National Cancer Institute. 
U.S. Preventive Services Task Force.
Cervical Cancer from eMedicineHealth.

FDA: "FDA approves Gardasil 9 for prevention of certain cancers caused by five additional types of HPV."
The American College of Obstetricians and Gynecologists. “Cervical Cancer Screening.” July, 2014.
American Cancer Society. “American Cancer Society Guidelines for the Early Detection of Cancer” and "Survival Rates for Cervical Cancer, by Stage."
U.S. Preventive Services Task Force. “Cervical Cancer: Screening.”

CDC.


 

Reviewed by Traci C. Johnson on January 13, 2020

SOURCE: 

 

National Cancer Institute. 
U.S. Preventive Services Task Force.
Cervical Cancer from eMedicineHealth.

FDA: "FDA approves Gardasil 9 for prevention of certain cancers caused by five additional types of HPV."
The American College of Obstetricians and Gynecologists. “Cervical Cancer Screening.” July, 2014.
American Cancer Society. “American Cancer Society Guidelines for the Early Detection of Cancer” and "Survival Rates for Cervical Cancer, by Stage."
U.S. Preventive Services Task Force. “Cervical Cancer: Screening.”

CDC.


 

Reviewed by Traci C. Johnson on January 13, 2020

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When do cervical cancer occur?

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