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How does allogeneic stem cell transplant help in treating chronic myelogenous leukemia?

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Allogeneic stem cell transplant is the only potential cure for chronic myelogenous leukemia (CML). The procedure is usually done if you're young and don't have any medical issues besides CML. It replaces abnormal white blood cells with stem cells you get from a donor and lets your body make healthy blood cells. But there are serious risks, including a disease called GVHD (graft-versus-host disease). When this happens, the new stem cells attack your normal cells by mistake.

SOURCES:

American Cancer Society: "Treatment of Chronic Myeloid Leukemia by Phase."

The Leukemia & Lymphoma Society: "Chronic Myelogenous Leukemia."

Goldman, L. and Ausiello, D., eds.  , 23rd ed. Saunders Elsevier; 2007. Cecil Medicine

Baccarani, M.  , May 4, 2009. Annals of Oncology

FDA website.

ARIAD Pharmaceuticals Inc.

Reviewed by Laura J. Martin on January 3, 2018

SOURCES:

American Cancer Society: "Treatment of Chronic Myeloid Leukemia by Phase."

The Leukemia & Lymphoma Society: "Chronic Myelogenous Leukemia."

Goldman, L. and Ausiello, D., eds.  , 23rd ed. Saunders Elsevier; 2007. Cecil Medicine

Baccarani, M.  , May 4, 2009. Annals of Oncology

FDA website.

ARIAD Pharmaceuticals Inc.

Reviewed by Laura J. Martin on January 3, 2018

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