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What are the causes of mantle cell lymphoma?

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Doctors aren't sure why people get mantle cell lymphoma.

You can't catch it like you do a virus or cold. But scientists believe that most people with this disease, and other lymphomas that affect B-cell lymphocytes, share a mutation or change in some of their genes.

This change triggers the release of a protein called cyclin D1, which is in charge of cell growth. Too much leads to the uncontrolled growth of a certain type of B cell, causing mantle cell lymphoma.

Men get mantle cell lymphoma more often than women. The average age of patients with this form of cancer is the early 60s.

From: Mantle Cell Lymphoma WebMD Medical Reference

SOURCES:

American Cancer Society: "Types of Non-Hodgkin Lymphoma."

Cancercare.org: "Mantle Cell Lymphoma and New Treatments on the Horizon."

Leukemia & Lymphoma Society: "Get Information and Support," "Mantle Cell Lymphoma Facts."

Harvard Health Publications, Harvard Medical School: "Lymph Node Biopsy."

Reviewed by Laura J. Martin on February 03, 2019

SOURCES:

American Cancer Society: "Types of Non-Hodgkin Lymphoma."

Cancercare.org: "Mantle Cell Lymphoma and New Treatments on the Horizon."

Leukemia & Lymphoma Society: "Get Information and Support," "Mantle Cell Lymphoma Facts."

Harvard Health Publications, Harvard Medical School: "Lymph Node Biopsy."

Reviewed by Laura J. Martin on February 03, 2019

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What are the symptoms of mantle cell lymphoma?

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