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What gene tests can help diagnose acute myeloid leukemia (AML)?

ANSWER

Acute myeloid leukemia (AML) is a type of cancer that keeps immature stem cells from growing into healthy blood cells. There are several forms of AML. Your doctor can find out which one you have by looking for gene changes in a sample of your blood or bone marrow. Tests include:

  • Cytogenetic analysis looks for chromosome changes in your cells.
  • Immunophenotyping tests look for substances called markers on the surface of leukemia cells.
  • Fluorescent in situ hybridization (FISH) looks for abnormal chromosomes in your cells using special dyes that attach to certain parts of the chromosome.
  • Polymerase chain reaction (PCR) uses chemicals to find changes in genes.

SOURCES:

American Cancer Society: "How Is Acute Myeloid Leukemia Classified?" "How is Acute Myeloid Leukemia Diagnosed?"

American Society for Clinical Oncology: "Leukemia -- Acute Myeloid -- AML -- Diagnosis," "Leukemia -- Acute Myeloid -- AML -- Subtypes."

Mayo Clinic: "Acute myelogenous leukemia (AML): Tests and diagnosis."

National Cancer Institute: "Adult Acute Myeloid Leukemia Treatment (PDQ) - Patient Version."

Seattle Cancer Care Alliance: "Acute Myeloid Leukemia Symptoms & Diagnosis."

Reviewed by Laura J. Martin on March 13, 2017

SOURCES:

American Cancer Society: "How Is Acute Myeloid Leukemia Classified?" "How is Acute Myeloid Leukemia Diagnosed?"

American Society for Clinical Oncology: "Leukemia -- Acute Myeloid -- AML -- Diagnosis," "Leukemia -- Acute Myeloid -- AML -- Subtypes."

Mayo Clinic: "Acute myelogenous leukemia (AML): Tests and diagnosis."

National Cancer Institute: "Adult Acute Myeloid Leukemia Treatment (PDQ) - Patient Version."

Seattle Cancer Care Alliance: "Acute Myeloid Leukemia Symptoms & Diagnosis."

Reviewed by Laura J. Martin on March 13, 2017

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What treatments work on acute myeloid leukemia (AML)?

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