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How do bisphosphonates treat multiple myeloma pain?

ANSWER

People with multiple myeloma have many options to help with pain.

Bisphosphonates are medicines commonly used to treat and prevent osteoporosis. They can slow bone loss, decrease bone pain, and lower your chances of a fracture. At least one monoclonal antibody, denosumab (Xgeva), has been found to interrupt or even stop the cells which are causing bones to break down.

SOURCES:

Multiple Myeloma Research Foundation: "Bone Lesions and Damage," "Bone Marrow Tests," "Kyphoplasty," "Multiple Myeloma Tests," "Orthopedic Interventions," "Vertebroplasty," "What are bisphosphonates?"

National Comprehensive Cancer Network: "About multiple myeloma."

Sigurdur, K., Minter, A., Korde, N., Tan, E., Landgren, O. , published online May 1, 2012. Bone disease in multiple myeloma and precursor disease: novel diagnostic approaches and implications on clinical management

University of Pennsylvania Health System: "All About Multiple Myeloma."

U.S. Food and Drug Administration: "Bisphosphonates (marketed as Actonel, Actonel+Ca, Aredia, Boniva, Didronel, Fosamax, Fosamax+D, Reclast, Skelid, and Zometa) Information."

Reviewed by Laura J. Martin on October 2, 2018

WAS THIS ANSWER HELPFUL

SOURCES:

Multiple Myeloma Research Foundation: "Bone Lesions and Damage," "Bone Marrow Tests," "Kyphoplasty," "Multiple Myeloma Tests," "Orthopedic Interventions," "Vertebroplasty," "What are bisphosphonates?"

National Comprehensive Cancer Network: "About multiple myeloma."

Sigurdur, K., Minter, A., Korde, N., Tan, E., Landgren, O. , published online May 1, 2012. Bone disease in multiple myeloma and precursor disease: novel diagnostic approaches and implications on clinical management

University of Pennsylvania Health System: "All About Multiple Myeloma."

U.S. Food and Drug Administration: "Bisphosphonates (marketed as Actonel, Actonel+Ca, Aredia, Boniva, Didronel, Fosamax, Fosamax+D, Reclast, Skelid, and Zometa) Information."

Reviewed by Laura J. Martin on October 2, 2018

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