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Can chemotherapy help metastatic pancreatic cancer?

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Chemotherapy can also help improve pancreatic cancer symptoms and survival. Gemcitabine (Gemzar) has been the most wildly used chemotherapy drug for treating metastatic pancreas cancer. Other drug combinations include gemcitabine with erlotinib (Tarceva), gemcitabine with capecitabine (Xeloba), gemcitabine with cisplatin, and gemcitabine with nab-paclitaxel. If you’re in fairly good health you may receive FOLFIRINOX (5-FU/leucovorin/oxaliplatin/irinotecan). Other combinations include gemcitabine alone or with another agent like (nab)-paclitaxel or capecitabine. Next line drug combinations to treat pancreatic cancer include oxaliplatin/fluoropyrimidine, or irinotecan liposome (Onivyde) in combination with fluorouracil plus leucovorin. The drug olaparib (Lynparza) has been approved for metastatic patients with the BRCA gene mutation whose cancer has responded well to chemotherapy.

SOURCES:

American Cancer Society: "Detailed Guide: Pancreatic Cancer."

National Cancer Institute: "Pancreatic Cancer."

Gunturu, KS. , March 2013. Med Oncol

 

Reviewed by Michael Dansinger on January 26, 2020

SOURCES:

American Cancer Society: "Detailed Guide: Pancreatic Cancer."

National Cancer Institute: "Pancreatic Cancer."

Gunturu, KS. , March 2013. Med Oncol

 

Reviewed by Michael Dansinger on January 26, 2020

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What clinical trials are done for pancreatic cancer?

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