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How does pancreatic cancer develop?

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Pancreatic cancer develops when a cell in the pancreas acquires damage to its DNA that causes it to behave and multiply abnormally. A single cancer cell grows and divides rapidly, becoming a tumor that does not respect normal boundaries in the body. Eventually, cells from the tumor travel elsewhere in the body (metastasize) through the blood or lymphatic system.

SOURCES:

Klein A.P. , July-August 2001; vol 7: pp 266-73. The Cancer Journal

Tersmette A.C. March 2001; vol 7: pp 738-44. Clinical Cancer Research,

Fuchs C.S. , Oct. 28, 1996; vol 156: pp 2255-60. Archives of Internal Medicine

Chari S.T. . January 2008; vol 134: pp 95-101. Gastroenterology

Michaud D.S. , Aug. 22-29, 2001; vol 286: pp 921-9. The Journal of the American Medical Association

Michaud D.S. , April 6, 2005; vol 97: pp 518-24. Journal of the National Cancer Institute

Reviewed by Minesh Khatri on July 24, 2017

SOURCES:

Klein A.P. , July-August 2001; vol 7: pp 266-73. The Cancer Journal

Tersmette A.C. March 2001; vol 7: pp 738-44. Clinical Cancer Research,

Fuchs C.S. , Oct. 28, 1996; vol 156: pp 2255-60. Archives of Internal Medicine

Chari S.T. . January 2008; vol 134: pp 95-101. Gastroenterology

Michaud D.S. , Aug. 22-29, 2001; vol 286: pp 921-9. The Journal of the American Medical Association

Michaud D.S. , April 6, 2005; vol 97: pp 518-24. Journal of the National Cancer Institute

Reviewed by Minesh Khatri on July 24, 2017

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How does DNA damage lead to pancreatic cancer?

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