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How can nongenetic information help with tailored medicine?

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Nongenetic information is important for research that can lead to new effective treatments. For example, with many conditions, only some people with genetic changes linked to a disease actually get the disease. That could mean things like where you live played a role in whether or not a gene was “turned on” and led to a disease.

SOURCES:

The White House: "Fact Sheet: President Obama's Precision Medicine Initiative.”

National Institutes of Health/All of Us Research Program: "About the Precision Medicine Initiative," “Data and Research Center.”

American Cancer Society: “Personalized Medicine: Redefining Cancer and Its Treatment.”

Elizabeth A. McGlynn, PhD, vice president, Kaiser Permanente Research, Oakland, CA.

Milan Radovich, PhD, medical co-director, Indiana University/IU Health Precision Genomics Program, Indianapolis.

Eric Dishman, director, All of Us Research Program, National Institutes of Health.

NIH Genetics Home Reference: "Do all gene mutations affect health and development?"

University of Utah Genetic Science Learning Center: "More Examples of Precision Medicine in Action."

Stefan C. Grant, MD, associate professor, hematology & oncology, Wake Forest Baptist Medical Center, Winston-Salem, NC.

Intermountain Healthcare: "Talking to Your Doctor: Precision Medicine."

Reviewed by Arefa Cassoobhoy on December 26, 2019

SOURCES:

The White House: "Fact Sheet: President Obama's Precision Medicine Initiative.”

National Institutes of Health/All of Us Research Program: "About the Precision Medicine Initiative," “Data and Research Center.”

American Cancer Society: “Personalized Medicine: Redefining Cancer and Its Treatment.”

Elizabeth A. McGlynn, PhD, vice president, Kaiser Permanente Research, Oakland, CA.

Milan Radovich, PhD, medical co-director, Indiana University/IU Health Precision Genomics Program, Indianapolis.

Eric Dishman, director, All of Us Research Program, National Institutes of Health.

NIH Genetics Home Reference: "Do all gene mutations affect health and development?"

University of Utah Genetic Science Learning Center: "More Examples of Precision Medicine in Action."

Stefan C. Grant, MD, associate professor, hematology & oncology, Wake Forest Baptist Medical Center, Winston-Salem, NC.

Intermountain Healthcare: "Talking to Your Doctor: Precision Medicine."

Reviewed by Arefa Cassoobhoy on December 26, 2019

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