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How do bisphosphonates work to treat bone metastasis?

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  • This group of drugs works best in cases where metastasis is weakening the bone. You receive bisphosphonates by mouth or IV infusion every 3 to 4 weeks. These drugs help with bone metastasis by: Slowing bone damage and reducing the risk of bone fractures
  • Easing bone pain
  • Reducing high levels of calcium in the blood

From: Treating Bone Metastasis WebMD Medical Reference

SOURCES:

American Cancer Society: "Bone Metastasis Overview;" "Immunotherapy;" and "Possible side effects of radiation therapy."

Dubey, A. 2010. The Internet Journal of Pain, Symptom Control and Palliative Care,

Society of Interventional Radiology: "Nonsurgical Treatments for Metastatic Cancer in Bones."

Catanel, A. 2007. Annals of Oncology,

Napoli, A. 2013. RadioGraphics,

BlueCross BlueShield of North Carolina: "Corporate Medical Policy: MRI-Guided Focused Ultrasound."

Reviewed by Laura J. Martin on July 30, 2017

SOURCES:

American Cancer Society: "Bone Metastasis Overview;" "Immunotherapy;" and "Possible side effects of radiation therapy."

Dubey, A. 2010. The Internet Journal of Pain, Symptom Control and Palliative Care,

Society of Interventional Radiology: "Nonsurgical Treatments for Metastatic Cancer in Bones."

Catanel, A. 2007. Annals of Oncology,

Napoli, A. 2013. RadioGraphics,

BlueCross BlueShield of North Carolina: "Corporate Medical Policy: MRI-Guided Focused Ultrasound."

Reviewed by Laura J. Martin on July 30, 2017

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What are possible side effects of bisphosphonates for bone metastasis?

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