PREVIOUS QUESTION:

 

NEXT QUESTION:

 

How do targeted therapies work to fight cancer?

ANSWER

Along with the classic cancer treatments -- radiation, surgery, and chemotherapy -- scientists now have targeted therapies for a number of tumor types. Rather than killing all cells that, like cancer cells, quickly divide, these drugs home in on tumor cells that have certain changes or molecules. Targeted therapies can change the way a tumor interacts with your immune system, weakening the cancer. Scientists are studying whether adding immunotherapy to targeted drugs can make them more powerful.

From: Combination Care for Cancer WebMD Medical Reference

SOURCES:

Dana-Farber Cancer Institute: “What is Combination Therapy?”

University of Texas M.D. Anderson Cancer Center: “Nivolumab with chemotherapy improves response, survival in AML study patients.”

Clinical and Translational Science : “Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities.”

American Association for Cancer Research: “Stepping Into the Era of Combination Cancer Therapies, Part 1: Combining Immunotherapies.”

American Cancer Society: “What is Cancer Immunotherapy?”

Journal of Experimental Medicine : “Combination immunotherapy for cancer.”

Memorial Sloan Kettering Cancer Center: “FDA Approves An MSK-Pioneered Combination Of Two Cancer-Fighting Drugs.”

Cancer Research Institute: “About Clinical Trials.”

National Cancer Institute: “Immunotherapy,” “Radiation Therapy for Cancer.”

Future Oncology : “The Promise of Combining Radiation Therapy and Immunotherapy.”

Weill Cornell Medicine: “The promise of combining radiotherapy and immunotherapy to treat cancer.”

Cancer Research : “Autophagy Induced by Conventional Chemotherapy Mediates Tumor Cell Sensitivity to Immunotherapy.”

Oncology Live : “Nivolumab Plus Chemotherapy Shows Similar Efficacy to Nivolumab Monotherapy in NSCLC.”

Nature Reviews Cancer : “Combining immunotherapy and targeted therapies in cancer treatment.”

Macmillan Cancer Support: “Nivolumab (OPDIVO).”

National Cancer Institute: "FDA Approves Nivolumab and Ipilimumab Combination for Advanced Kidney Cancer," "Combination of Immunotherapy Drugs Approved for Metastatic Colorectal Cancer."

Reviewed by Laura J. Martin on January 20, 2019

SOURCES:

Dana-Farber Cancer Institute: “What is Combination Therapy?”

University of Texas M.D. Anderson Cancer Center: “Nivolumab with chemotherapy improves response, survival in AML study patients.”

Clinical and Translational Science : “Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities.”

American Association for Cancer Research: “Stepping Into the Era of Combination Cancer Therapies, Part 1: Combining Immunotherapies.”

American Cancer Society: “What is Cancer Immunotherapy?”

Journal of Experimental Medicine : “Combination immunotherapy for cancer.”

Memorial Sloan Kettering Cancer Center: “FDA Approves An MSK-Pioneered Combination Of Two Cancer-Fighting Drugs.”

Cancer Research Institute: “About Clinical Trials.”

National Cancer Institute: “Immunotherapy,” “Radiation Therapy for Cancer.”

Future Oncology : “The Promise of Combining Radiation Therapy and Immunotherapy.”

Weill Cornell Medicine: “The promise of combining radiotherapy and immunotherapy to treat cancer.”

Cancer Research : “Autophagy Induced by Conventional Chemotherapy Mediates Tumor Cell Sensitivity to Immunotherapy.”

Oncology Live : “Nivolumab Plus Chemotherapy Shows Similar Efficacy to Nivolumab Monotherapy in NSCLC.”

Nature Reviews Cancer : “Combining immunotherapy and targeted therapies in cancer treatment.”

Macmillan Cancer Support: “Nivolumab (OPDIVO).”

National Cancer Institute: "FDA Approves Nivolumab and Ipilimumab Combination for Advanced Kidney Cancer," "Combination of Immunotherapy Drugs Approved for Metastatic Colorectal Cancer."

Reviewed by Laura J. Martin on January 20, 2019

NEXT QUESTION:

How will I know if immunotherapy is right for treating my cancer?

WAS THIS ANSWER HELPFUL

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

    This tool does not provide medical advice. See additional information.