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Are there different types of immunotherapy?

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Not all immunotherapies work the same. Some of these drugs boost immune system activity in a broad way, while others aim to teach your immune system to attack very specific cell types found in tumors. They include:

Each drug has different benefits and risks and is used in different circumstances.

  • CAR T-cell therapy
  • TCR therapy
  • TIL therapy
  • Monoclonal antibodies (naked, conjugate, and bispecific)
  • Immune checkpoint inhibitors (PD-1 or PD-L1, and CTLA-4)
  • Cancer vaccines
  • Interleukins
  • Interferons
  • Colony stimulating factors

From: Types of Immunotherapy WebMD Medical Reference

SOURCES:

American Cancer Society: “Cancer Vaccines,” “Immune checkpoint inhibitors to treat cancer,” “Monoclonal antibodies to treat cancer,” “Non-specific cancer immunotherapies and adjuvants,” “What is cancer immunotherapy?” “What’s new in cancer immunotherapy research?”

National Cancer Institute: “Immunotherapy.”

Mayo Clinic: “What cancers may be treated with monoclonal antibody drugs?”

Rambam Maimonides Medical Journal : “Adoptive T Cell Immunotherapy for Cancer.”

MD Anderson Cancer Center: “Immunotherapy.”

Reviewed by Laura J. Martin on January 20, 2019

SOURCES:

American Cancer Society: “Cancer Vaccines,” “Immune checkpoint inhibitors to treat cancer,” “Monoclonal antibodies to treat cancer,” “Non-specific cancer immunotherapies and adjuvants,” “What is cancer immunotherapy?” “What’s new in cancer immunotherapy research?”

National Cancer Institute: “Immunotherapy.”

Mayo Clinic: “What cancers may be treated with monoclonal antibody drugs?”

Rambam Maimonides Medical Journal : “Adoptive T Cell Immunotherapy for Cancer.”

MD Anderson Cancer Center: “Immunotherapy.”

Reviewed by Laura J. Martin on January 20, 2019

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