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Does polycythemia vera cause myelofibrosis and leukemia?

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Polycythemia vera causes your body to make too many red blood cells. After years of this, your bone marrow can become so filled with scar tissue that it can't make enough blood cells to meet your body's needs. Doctors call this condition myelofibrosis.

It’s rare, but abnormal bone marrow cells grow out of control. This can lead to acute myelogenous leukemia, a cancer of the blood and bone marrow.

Again, these problems aren’t likely. Your doctor will closely follow your health to make sure you’re doing well and staying free of complications.

SOURCES:

American College of Gastroenterology: "Peptic Ulcer Disease."

Cancer Care: "Managing Symptoms of Polycythemia Vera (PV)."

Khan, F. Anaesthesia, Pain & Intensive Care, 2012.

Leukemia & Lymphoma Society: "Myelofibrosis Facts."

Medscape: "Polycythemia Vera Clinical Presentation," "Polycythemia Vera Treatment & Management."

MPN Research Foundation: "What is Primary Myelofibrosis (MF)?"

National Heart, Lung, and Blood Institute: "How Is Polycythemia Vera Treated?" "What Are the Signs and Symptoms of Polycythemia Vera?"

National Institute of Arthritis and Musculoskeletal and Skin Diseases: "Questions and Answers About Gout."

National Organization for Rare Disorders: "Polycythemia Vera."

News release, FDA.

Patrono, C. Blood, 2013.

The Myeloproliferative Disorders Research Consortium: "FAQ: About Polycythemia Vera."

University of Iowa Hospitals & Clinics: "Polycythemia Vera."

Reviewed by Brunilda Nazario on October 19, 2020

SOURCES:

American College of Gastroenterology: "Peptic Ulcer Disease."

Cancer Care: "Managing Symptoms of Polycythemia Vera (PV)."

Khan, F. Anaesthesia, Pain & Intensive Care, 2012.

Leukemia & Lymphoma Society: "Myelofibrosis Facts."

Medscape: "Polycythemia Vera Clinical Presentation," "Polycythemia Vera Treatment & Management."

MPN Research Foundation: "What is Primary Myelofibrosis (MF)?"

National Heart, Lung, and Blood Institute: "How Is Polycythemia Vera Treated?" "What Are the Signs and Symptoms of Polycythemia Vera?"

National Institute of Arthritis and Musculoskeletal and Skin Diseases: "Questions and Answers About Gout."

National Organization for Rare Disorders: "Polycythemia Vera."

News release, FDA.

Patrono, C. Blood, 2013.

The Myeloproliferative Disorders Research Consortium: "FAQ: About Polycythemia Vera."

University of Iowa Hospitals & Clinics: "Polycythemia Vera."

Reviewed by Brunilda Nazario on October 19, 2020

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