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How is immunotherapy used for adoptive T cell transfer?

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In this treatment, the doctor takes T cells -- a type of white blood cell -- from your tumor. He or she will test them to find out which T cells are most active in fighting the cancer. Then the doctor will alter genes in those cells to make them more active and grow large batches of those cells in the lab. Finally, the supercharged T cells go back into your body through an IV infusion. The approach has shrunk some tumors in a range of cancers, including melanoma, leukemia, and prostate cancer.

From: Types of Immunotherapy WebMD Medical Reference

SOURCES:

American Cancer Society: “Cancer Vaccines,” “Immune checkpoint inhibitors to treat cancer,” “Monoclonal antibodies to treat cancer,” “Non-specific cancer immunotherapies and adjuvants,” “What is cancer immunotherapy?” “What’s new in cancer immunotherapy research?”

National Cancer Institute: “Immunotherapy.”

Mayo Clinic: “What cancers may be treated with monoclonal antibody drugs?”

Rambam Maimonides Medical Journal : “Adoptive T Cell Immunotherapy for Cancer.”

MD Anderson Cancer Center: “Immunotherapy.”

Reviewed by Laura J. Martin on January 20, 2019

SOURCES:

American Cancer Society: “Cancer Vaccines,” “Immune checkpoint inhibitors to treat cancer,” “Monoclonal antibodies to treat cancer,” “Non-specific cancer immunotherapies and adjuvants,” “What is cancer immunotherapy?” “What’s new in cancer immunotherapy research?”

National Cancer Institute: “Immunotherapy.”

Mayo Clinic: “What cancers may be treated with monoclonal antibody drugs?”

Rambam Maimonides Medical Journal : “Adoptive T Cell Immunotherapy for Cancer.”

MD Anderson Cancer Center: “Immunotherapy.”

Reviewed by Laura J. Martin on January 20, 2019

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