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What are possible side effects of bisphosphonate therapy for bone metastasis?

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  • Possible side effects of bisphosphonate therapy include: Fatigue
  • Fever
  • Nausea or vomiting
  • Anemia
  • Bone or joint pain A rare and serious side effect is bone death (osteonecrosis) of the jaw. Ask your doctor about precautions to take before beginning this treatment. Osteonecrosis may cause:
  • Jaw bone pain, swelling, or numbness
  • Loss of gum tissue
  • Loose teeth
  • Infection

From: Treating Bone Metastasis WebMD Medical Reference

SOURCES:

American Cancer Society: "Bone Metastasis Overview;" "Immunotherapy;" and "Possible side effects of radiation therapy."

Dubey, A. 2010. The Internet Journal of Pain, Symptom Control and Palliative Care,

Society of Interventional Radiology: "Nonsurgical Treatments for Metastatic Cancer in Bones."

Catanel, A. 2007. Annals of Oncology,

Napoli, A. 2013. RadioGraphics,

BlueCross BlueShield of North Carolina: "Corporate Medical Policy: MRI-Guided Focused Ultrasound."

Reviewed by Laura J. Martin on July 30, 2017

SOURCES:

American Cancer Society: "Bone Metastasis Overview;" "Immunotherapy;" and "Possible side effects of radiation therapy."

Dubey, A. 2010. The Internet Journal of Pain, Symptom Control and Palliative Care,

Society of Interventional Radiology: "Nonsurgical Treatments for Metastatic Cancer in Bones."

Catanel, A. 2007. Annals of Oncology,

Napoli, A. 2013. RadioGraphics,

BlueCross BlueShield of North Carolina: "Corporate Medical Policy: MRI-Guided Focused Ultrasound."

Reviewed by Laura J. Martin on July 30, 2017

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