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What causes gastroesophageal (GE) junction adenocarcinoma?

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No one knows exactly what causes GE junction adenocarcinoma. It might be that irritation in your esophagus causes healthy cells to turn into cancer.

You may be more likely to get it if you:

This type of cancer is most common in white men, although women get it, too.

  • Have gastroesophageal reflux disease (GERD)
  • Have Barrett's esophagus, a problem with the tissue that lines the inside of your esophagus
  • Are obese
  • Smoke
  • Don't eat enough fruit and vegetables

SOURCES:

American Cancer Society: "Key Statistics for Esophageal Cancer," "Living as an Esophagus Cancer Survivor," "Radiation Therapy for Esophageal Cancer," "Surgery for Esophageal Cancer," "Targeted Therapy for Esophageal Cancer," "Tests for Esophageal Cancer," "What is Cancer of the Esophagus?"

Annals of Thoracic Surgery : "The Society of Thoracic Surgeons guidelines on the diagnosis and staging of patients with esophageal cancer."

Cancer.Net: "Esophageal Cancer: Questions to Ask the Doctor."

Cancer Research UK: "About gastro oesophageal junction cancer," "Survival," "Treatment for gastro oesophageal junction cancer."

Cleveland Clinic: "Esophageal Cancer."

Johns Hopkins Medicine: "The Migration of Gastric Cancer to the GE Junction."

Medscape: "Esophageal Cancer."

NHS: "Living with oesophageal cancer."

Radiation Oncology : "Clinical management of gastroesophageal junction tumors: past and recent evidences for the role of radiotherapy in the multidisciplinary approach."

Reviewed by Laura J. Martin on November 06, 2017

SOURCES:

American Cancer Society: "Key Statistics for Esophageal Cancer," "Living as an Esophagus Cancer Survivor," "Radiation Therapy for Esophageal Cancer," "Surgery for Esophageal Cancer," "Targeted Therapy for Esophageal Cancer," "Tests for Esophageal Cancer," "What is Cancer of the Esophagus?"

Annals of Thoracic Surgery : "The Society of Thoracic Surgeons guidelines on the diagnosis and staging of patients with esophageal cancer."

Cancer.Net: "Esophageal Cancer: Questions to Ask the Doctor."

Cancer Research UK: "About gastro oesophageal junction cancer," "Survival," "Treatment for gastro oesophageal junction cancer."

Cleveland Clinic: "Esophageal Cancer."

Johns Hopkins Medicine: "The Migration of Gastric Cancer to the GE Junction."

Medscape: "Esophageal Cancer."

NHS: "Living with oesophageal cancer."

Radiation Oncology : "Clinical management of gastroesophageal junction tumors: past and recent evidences for the role of radiotherapy in the multidisciplinary approach."

Reviewed by Laura J. Martin on November 06, 2017

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What are symptoms of gastroesophageal (GE) junction adenocarcinoma?

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