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What causes nerve sheath tumors?

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Doctors don't know what causes most schwannomas and neurofibrosarcomas. However, nerve sheath tumors are more common in people who have the inherited disorder neurofibromatosis type 1 (previously known as von Recklinghausen disease).

Vestibular schwannomas are linked to neurofibromatosis type 2. Having a genetic disorder called schwannomatosis also can increase the risk for schwannomas. A small percentage of neurofibrosarcomas are related to past radiation exposure.

From: Neurofibrosarcoma and Schwannoma WebMD Medical Reference

SOURCES:

Cincinnati Brain Tumor Center: "Nerve Sheath Tumors."

The University Hospital: "Treatment of NF1."

Children's Hospital Boston: "Peripheral Nerve Sheath Tumor (Neurofibrosarcoma)."

Neville H. ; March 2003. Journal of Pediatric Surgery

Acoustic Neuroma Association: "What is Acoustic Neuroma."

National Institute on Deafness and Other Communication Disorders.:"Vestibular Schwannoma (Acoustic Neuroma) and Neurofibromatosis."

Fletcher, Christopher D.M. , 3rd ed., Philadelphia, Saunders Elsevier; 2007. Diagnostic Histopathology of Tumors

Reviewed by Jennifer Robinson on November 25, 2018

SOURCES:

Cincinnati Brain Tumor Center: "Nerve Sheath Tumors."

The University Hospital: "Treatment of NF1."

Children's Hospital Boston: "Peripheral Nerve Sheath Tumor (Neurofibrosarcoma)."

Neville H. ; March 2003. Journal of Pediatric Surgery

Acoustic Neuroma Association: "What is Acoustic Neuroma."

National Institute on Deafness and Other Communication Disorders.:"Vestibular Schwannoma (Acoustic Neuroma) and Neurofibromatosis."

Fletcher, Christopher D.M. , 3rd ed., Philadelphia, Saunders Elsevier; 2007. Diagnostic Histopathology of Tumors

Reviewed by Jennifer Robinson on November 25, 2018

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