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Which cells does a gastrointestinal-stromal tumor start in?

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A gastrointestinal-stromal tumor starts in nervous system cells in the wall of the GI tract -- called interstitial cells of Cajal. These cells send signals to the muscles in the digestive system to contract to move food and liquid through the system.

From: GIST: Frequently Asked Questions WebMD Medical Reference

SOURCES:

GSI. GIST Support International.

Demetri, G. . Published online July 6, 2007. Journal of the National Comprehensive Cancer Network

Demetri, G. . (Update to above). Published 2010. Journal of the National Comprehensive Cancer Network

American Cancer Society.

American Society of Clinical Oncology.

U.S. Food and Drug Administration. Gleevec Prescribing Information.  

News release, FDA.

Reviewed by Laura J. Martin on July 11, 2018

SOURCES:

GSI. GIST Support International.

Demetri, G. . Published online July 6, 2007. Journal of the National Comprehensive Cancer Network

Demetri, G. . (Update to above). Published 2010. Journal of the National Comprehensive Cancer Network

American Cancer Society.

American Society of Clinical Oncology.

U.S. Food and Drug Administration. Gleevec Prescribing Information.  

News release, FDA.

Reviewed by Laura J. Martin on July 11, 2018

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How does gastrointestinal-stromal tumors progress?

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