What Is the National Comprehensive Cancer Network?

Medically Reviewed by Melinda Ratini, DO, MS on January 20, 2022

The National Comprehensive Cancer Network (NCCN) is a nonprofit alliance of 31 cancer centers throughout the U.S. Experts from NCCN cancer centers diagnose and treat all cancers, with a particular focus on complex, aggressive, or uncommon cancers.

The National Comprehensive Cancer Network also develops the NCCN Clinical Practice Guidelines in Oncology, a set of recommendations designed to help health care professionals diagnose, treat, and manage cancer patient care. These guidelines have also been translated into the NCCN Treatment Summaries for People with Cancer, which help people with cancer better understand cancer diagnosis and treatment options.

The 31 Cancer Centers Comprising the NCCN

Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute
Cleveland, Ohio
(216) 844-8797
[email protected]

City of Hope Comprehensive Cancer Center
Los Angeles, CA
(800) 826-4673

Dana-Farber/Brigham and Women’s Cancer Center│Massachusetts General Hospital Cancer Center
Boston, MA
(800) 320-0022

Duke Comprehensive Cancer Center
Durham, NC
(888) 275-3853

Fox Chase Cancer Center
Philadelphia, PA
(888) 369-2427

Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance
Seattle, WA
(800) 804-8824
(206) 288-7222 (SCCA)

The Fred & Pamela Buffett Cancer Center -- Nebraska Medicine and the University of Nebraska Medical Center (UNMC)
Omaha, Nebraska
(800) 999-5465

H. Lee Moffitt Cancer Center & Research Institute
Tampa, FL
(800) 456-3434

Huntsman Cancer Institute at the University of Utah
Salt Lake City, UT
(877) 585-0303

Mayo Clinic Cancer Center
Phoenix/Scottsdale, AZ; Jacksonville, FL, Rochester, MN
(800) 446-2279

Memorial Sloan Kettering Cancer Center
New York, NY
(800) 525-2225

Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute
Columbus, OH
(800) 293-5066

Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Chicago, IL
(866) 587-4322

Roswell Park Cancer Institute
Buffalo, NY
(877) 275-7724

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, MD
(410) 955-8964

Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine
St. Louis, MO
(800) 600-3606

Stanford Comprehensive Cancer Center
Stanford, CA
(877) 668-7535

St. Jude Children’s Research Hospital/University of Tennessee Cancer Institute
Memphis, TN
(901) 595-4055 (St. Jude)
(877) 988-3627 (UTCI)

UC San Diego Moores Cancer Center
La Jolla, CA
(858) 657-7000

UCSF Helen Diller Family Comprehensive Cancer Center
San Francisco, CA
(800) 888-8664

University of Alabama at Birmingham Comprehensive Cancer Center
Birmingham, AL
(800) 822-0933

University of Colorado Cancer Center
Aurora, CO
(720) 848-0300

University of Michigan Comprehensive Cancer Center
Ann Arbor, MI
(800) 865-1125

Vanderbilt-Ingram Cancer Center
Nashville, TN
(800) 811-8480

Yale Cancer Center/Smilow Cancer Hospital
New Haven, CT
(855)-4-SMILOW (476-4569

The NCCN Clinical Practice Guidelines in Oncology

The NCCN Clinical Practice Guidelines in Oncology detail cancer management decisions and interventions for most cancers. The recommendations are based on the best evidence available, so they are continuously updated and revised to reflect new and promising research. The goal of the guidelines is to help oncologists make major treatment decisions for patients by providing quick access to data.