Nov. 9, 2007 -- It may be possible to predict which kids are most likely to mature into adults with type 2 diabetes -- and to nip that risk in the bud.
A new study spotlights two key strategies:
- Start early. Watch for type 2 diabetes risk factors beginning in childhood.
- Manage weight for a lifetime.
People with metabolic syndrome have at least three of these traits:
- Large waist
- Above-normal blood pressure
- Above-normal blood sugar (glucose) after fasting
- Above-normal triglycerides (a type of fat in the blood) after fasting
- Below-normal HDL ("good") cholesterol
The new study started in the 1970s and spanned a quarter of a century.
Some 25-30 years later, the participants got another checkup. This time, a quarter of them were overweight, 26% had metabolic syndrome, and about 5% had type 2 diabetes.
Type 2 diabetes was most common among the following groups:
- Adults who had metabolic syndrome as kids
- Adults who had a parental history of diabetes
- African-Americans, who were twice as likely as whites to have type 2 diabetes as adults
- Older adults (diabetes becomes more likely with age)
At all ages, being overweight made metabolic syndrome more likely, and overweight kids often became overweight adults.
The researchers, who included John Morrison, PhD, of Cincinnati Children's Hospital Medical Center, conclude that kids aged 5-19 should be checked for metabolic syndrome and parental history of diabetes.
Morrison's team also emphasizes the importance of weight management to make metabolic syndrome and diabetes less likely.
The study appears online in The Journal of Pediatrics.