PREVIOUS QUESTION:

 

NEXT QUESTION:

 

What are the symptoms of familial partial lipodystrophy (FPL) in women?

ANSWER

It's easier to recognize familial partial lipodystrophy (FPL) in women, since men tend to look muscular even without the disease. About one-quarter of women get more body hair. They can also have problems with their periods and may get polycystic ovary syndrome (PCOS). These women are more likely to have serious complications including:

  • Diabetes
  • High triglyceride and low HDL (the "good" cholesterol) levels
  • Heart disease

From: Inherited Lipodystrophy WebMD Medical Reference

SOURCES:

NORD Physician Guides: "Lipodystrophy Disorders."

FDA: "FDA approves Myalept to treat rare metabolic disease."

Lipodystrophy United: "About Lipodystrophy."

University of Texas Southwestern Medical Center: "Lipodystrophy," "Lipodystrophy Therapies."

Genetics Home Reference: "Berardinelli-Seip congenital lipodystrophy."

KidsHealth: "Acanthosis Nigricans."

AACE Lipodystrophy Detection Consensus Statement, , January-February 2013. Endocrine Practice

Endocrine Society, Resource Room Slide Series: "Lipodystrophy: Metabolic and Clinical Aspects."

DermNet NZ: "Lipodystrophy."

Orphanet: "Berardinelli-Seip congenital lipodystrophy," "Familial partial lipodystrophy, Köbberling type," "Familial partial lipodystrophy, Dunnigan type," "Familial partial lipodystrophy associated with PPARG mutations."

Reviewed by Melinda Ratini on February 10, 2017

WAS THIS ANSWER HELPFUL

SOURCES:

NORD Physician Guides: "Lipodystrophy Disorders."

FDA: "FDA approves Myalept to treat rare metabolic disease."

Lipodystrophy United: "About Lipodystrophy."

University of Texas Southwestern Medical Center: "Lipodystrophy," "Lipodystrophy Therapies."

Genetics Home Reference: "Berardinelli-Seip congenital lipodystrophy."

KidsHealth: "Acanthosis Nigricans."

AACE Lipodystrophy Detection Consensus Statement, , January-February 2013. Endocrine Practice

Endocrine Society, Resource Room Slide Series: "Lipodystrophy: Metabolic and Clinical Aspects."

DermNet NZ: "Lipodystrophy."

Orphanet: "Berardinelli-Seip congenital lipodystrophy," "Familial partial lipodystrophy, Köbberling type," "Familial partial lipodystrophy, Dunnigan type," "Familial partial lipodystrophy associated with PPARG mutations."

Reviewed by Melinda Ratini on February 10, 2017

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

    This tool does not provide medical advice. See additional information.