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What happens in trisomy 13?

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The additional chromosome can come from either the egg or the sperm, but doctors think that the chances a woman will have a baby with any chromosome abnormality go up after age 35.

The extra 13th chromosome damages normal development, and causes the features of trisomy 13, including severe mental and physical problems. Unfortunately, most babies born with it don’t live past their first month or year. But some can survive for years.

That’s because there are two different kinds of trisomy 13. Babies can have three copies of chromosome number 13 in all of their cells, or in only some of them. The symptoms depend on how many cells have the extra chromosome.

From: What Is Trisomy 13? WebMD Medical Reference

SOURCES:

Centre for Genetics Education: “Trisomy 13: Patau Syndrome.”

Dugo, N. , January-March 2014. Journal of Prenatal Medicine

Genetic and Rare Diseases Information Center: “Trisomy 13.”

The Mayo Clinic: “High Blood Pressure (Hypertension).”

National Institute of Arthritis and Musculoskeletal and Skin Diseases: “Scoliosis.”

National Organization for Rare Disorders: “Trisomy 13 Syndrome.”

Trisomy.org: “Trisomy 13 Facts” and “Care of the Infant and Child with Trisomy 18 or Trisomy 1.”

U.S. National Library of Medicine: “What is a Chromosome?”, “What is DNA?” and “Trisomy 13.”

University of Rochester Medical Center: “Trisomy 18 and 13.”

Reviewed by Renee A. Alli on September 09, 2018

SOURCES:

Centre for Genetics Education: “Trisomy 13: Patau Syndrome.”

Dugo, N. , January-March 2014. Journal of Prenatal Medicine

Genetic and Rare Diseases Information Center: “Trisomy 13.”

The Mayo Clinic: “High Blood Pressure (Hypertension).”

National Institute of Arthritis and Musculoskeletal and Skin Diseases: “Scoliosis.”

National Organization for Rare Disorders: “Trisomy 13 Syndrome.”

Trisomy.org: “Trisomy 13 Facts” and “Care of the Infant and Child with Trisomy 18 or Trisomy 1.”

U.S. National Library of Medicine: “What is a Chromosome?”, “What is DNA?” and “Trisomy 13.”

University of Rochester Medical Center: “Trisomy 18 and 13.”

Reviewed by Renee A. Alli on September 09, 2018

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How is trisomy 13 diagnosed?

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