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What is an immunoreactive trypsinogen (IRT) -based test?

ANSWER

The IRT-based test is a just a screening test -- it’s not meant to make a diagnosis. Most babies who “fail” the IRT screen don’t have cystic fibrosis -- they just have a higher risk and need another test to confirm. If results from the second test are normal, there’s no further risk or need for more testing.

SOURCES:

National Heart, Lung, and Blood Institute: “How is Cystic Fibrosis Diagnosed?”

Mayo Clinic: “Cystic Fibrosis.”

Cystic Fibrosis Foundation: “Newborn Screening for CF,” “Testing for CF,” Sweat Test.”

KidsHealth: “Cystic Fibrosis (CF) Chloride Sweat Test.”

March of Dimes: “Cystic fibrosis and pregnancy.”

NHS: “Causes of Cystic Fibrosis,” “Diagnosing Cystic Fibrosis.”

Reviewed by Dan Brennan on May 07, 2019

SOURCES:

National Heart, Lung, and Blood Institute: “How is Cystic Fibrosis Diagnosed?”

Mayo Clinic: “Cystic Fibrosis.”

Cystic Fibrosis Foundation: “Newborn Screening for CF,” “Testing for CF,” Sweat Test.”

KidsHealth: “Cystic Fibrosis (CF) Chloride Sweat Test.”

March of Dimes: “Cystic fibrosis and pregnancy.”

NHS: “Causes of Cystic Fibrosis,” “Diagnosing Cystic Fibrosis.”

Reviewed by Dan Brennan on May 07, 2019

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What is a "sweat test" to diagnose cystic fibrosis (CF)?

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