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Do genes contribute to fatigue syndrome?

ANSWER

Doctors don’t know the cause of chronic fatigue syndrome, but there are theories about things that may contribute to it.

Some studies have found abnormalities in the structure of certain genes. Other studies have found abnormalities in how some genes are turned on and off, inside cells.  Studies of identical and non-identical twins indicate that some people inherit a genetic susceptibility to getting the illness.

From: What is Chronic Fatigue Syndrome? WebMD Medical Reference

SOURCES:

CDC: “Chronic Fatigue Syndrome.”

Office of Women’s Health, U.S. Department of Health and Human Services: “Chronic fatigue syndrome.”

National Health Service (U.K.): “Chronic fatigue syndrome.”

Narita, M. , November 2003. Biochemical and Biophysical Research Communications

Sharpe, M. , July 1997. BMJ

Cleare, A. , April 2001. The American Journal of Psychiatry

Genetics Home Reference: “Corticosteroid-binding globulin deficiency.”

Reviewed by Anthony L Komaroff on October 12, 2018

SOURCES:

CDC: “Chronic Fatigue Syndrome.”

Office of Women’s Health, U.S. Department of Health and Human Services: “Chronic fatigue syndrome.”

National Health Service (U.K.): “Chronic fatigue syndrome.”

Narita, M. , November 2003. Biochemical and Biophysical Research Communications

Sharpe, M. , July 1997. BMJ

Cleare, A. , April 2001. The American Journal of Psychiatry

Genetics Home Reference: “Corticosteroid-binding globulin deficiency.”

Reviewed by Anthony L Komaroff on October 12, 2018

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Could infections or other illnesses contribute to chronic fatigue syndrome?

WAS THIS ANSWER HELPFUL

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

    This tool does not provide medical advice. See additional information.

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